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Phenolic Preservative Removal from Commercial Insulin Formulations Reduces Tissue Inflammation while Maintaining Euglycemia

[Image: see text] Background: Exogenous insulin therapy requires stabilization of the insulin molecule, which is achieved through the use of excipients (e.g., phenolic preservatives (PP)) that provide protein stability, sterility and prolong insulin shelf life. However, our laboratory recently repor...

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Argitaratua izan da:ACS Pharmacol Transl Sci
Egile Nagusiak: Mulka, Adam, Lewis, Brianne E., Mao, Li, Sharafieh, Roshanak, Kesserwan, Shereen, Wu, Rong, Kreutzer, Donald L., Klueh, Ulrike
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2021
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205237/
https://ncbi.nlm.nih.gov/pubmed/34151206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.1c00047
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