A carregar...

Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-dependent Kinase 2

While kinases have been attractive targets to combat many diseases including cancer, selective kinase inhibition has been challenging due to the high degree of structural homology in the active site, where many kinase inhibitors bind. We have previously discovered that 8-anilino-1-naphthalene sulfon...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Faber, Erik B., Tian, Defeng, Burban, David, Levinson, Nicholas M., Hawkinson, Jon E., Georg, Gunda I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204636/
https://ncbi.nlm.nih.gov/pubmed/32433863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00169
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!