Llwytho...
Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-dependent Kinase 2
While kinases have been attractive targets to combat many diseases including cancer, selective kinase inhibition has been challenging due to the high degree of structural homology in the active site, where many kinase inhibitors bind. We have previously discovered that 8-anilino-1-naphthalene sulfon...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | ACS Chem Biol |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204636/ https://ncbi.nlm.nih.gov/pubmed/32433863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00169 |
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