The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro

BACKGROUND: HSPB5 is an ATP-independent molecular chaperone that is induced by heat shock or other proteotoxic stresses. HSPB5 is cytoprotective against stress both intracellularly and extracellularly. It acts as a potential therapeutic candidate in ischemia-reperfusion and neurodegenerative disease...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Li, Jing, Yu, Jingjing, Xue, Wenxian, Huang, Huili, Yan, Longjun, Sang, Fan, An, Shuangshuang, Zhang, Jing, Wang, Mingli, Zhang, Jun, Li, Hui, Cui, Xiukun, He, Jiang, Hu, Yanzhong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204567/
https://ncbi.nlm.nih.gov/pubmed/34126963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-021-00700-y
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