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Empirical Bayes shrinkage and false discovery rate estimation, allowing for unwanted variation

We combine two important ideas in the analysis of large-scale genomics experiments (e.g. experiments that aim to identify genes that are differentially expressed between two conditions). The first is use of Empirical Bayes (EB) methods to handle the large number of potentially-sparse effects, and es...

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Detaylı Bibliyografya
Yayımlandı:Biostatistics
Asıl Yazarlar: Gerard, David, Stephens, Matthew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204175/
https://ncbi.nlm.nih.gov/pubmed/29985984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxy029
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