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Regulatory T-Cells as an Emerging Barrier to Immune Checkpoint Inhibition in Lung Cancer

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment paradigm for lung cancer in recent years. These strategies consist of neutralizing antibodies against negative regulators of immune function, most notably cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Principe, Daniel R., Chiec, Lauren, Mohindra, Nisha A., Munshi, Hidayatullah G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204014/
https://ncbi.nlm.nih.gov/pubmed/34141625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.684098
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