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Analysis of Direct Interaction between Viral DNA-binding Proteins by Protein Pull-down Co-immunoprecipitation Assay

This protocol analyzes the direct interaction between two DNA-binding proteins by pull-down co-immunoprecipitation. One of the proteins is overexpressed in E. coli as HA-tagged recombinant protein and cell-free extracts are immunoprecipitated in HA-affinity resin. Cell extracts are treated with nucl...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Lechuga, Ana, Berjón-Otero, Mónica, Salas, Margarita, Redrejo-Rodríguez, Modesto
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203933/
https://ncbi.nlm.nih.gov/pubmed/34179232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2678
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