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Engineered viral DNA polymerase with enhanced DNA amplification capacity: a proof-of-concept of isothermal amplification of damaged DNA

The development of whole genome amplification (WGA) and related methods, coupled with the dramatic growth of sequencing capacities, has changed the paradigm of genomic and genetic analyses. This has led to a continual requirement of improved DNA amplification protocols and the elaboration of new tai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ordóñez, Carlos D., Lechuga, Ana, Salas, Margarita, Redrejo-Rodríguez, Modesto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490695/
https://ncbi.nlm.nih.gov/pubmed/32929102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71773-6
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