DNA polymerase from temperate phage Bam35 is endowed with processive polymerization and abasic sites translesion synthesis capacity

DNA polymerases (DNAPs) responsible for genome replication are highly faithful enzymes that nonetheless cannot deal with damaged DNA. In contrast, translesion synthesis (TLS) DNAPs are suitable for replicating modified template bases, although resulting in very low-fidelity products. Here we report...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Berjón-Otero, Mónica, Villar, Laurentino, de Vega, Miguel, Salas, Margarita, Redrejo-Rodríguez, Modesto
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500267/
https://ncbi.nlm.nih.gov/pubmed/26100910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510280112
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