DNA polymerase from temperate phage Bam35 is endowed with processive polymerization and abasic sites translesion synthesis capacity

DNA polymerases (DNAPs) responsible for genome replication are highly faithful enzymes that nonetheless cannot deal with damaged DNA. In contrast, translesion synthesis (TLS) DNAPs are suitable for replicating modified template bases, although resulting in very low-fidelity products. Here we report...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Berjón-Otero, Mónica, Villar, Laurentino, de Vega, Miguel, Salas, Margarita, Redrejo-Rodríguez, Modesto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500267/
https://ncbi.nlm.nih.gov/pubmed/26100910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510280112
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