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DNA polymerase from temperate phage Bam35 is endowed with processive polymerization and abasic sites translesion synthesis capacity

DNA polymerases (DNAPs) responsible for genome replication are highly faithful enzymes that nonetheless cannot deal with damaged DNA. In contrast, translesion synthesis (TLS) DNAPs are suitable for replicating modified template bases, although resulting in very low-fidelity products. Here we report...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Berjón-Otero, Mónica, Villar, Laurentino, de Vega, Miguel, Salas, Margarita, Redrejo-Rodríguez, Modesto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500267/
https://ncbi.nlm.nih.gov/pubmed/26100910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510280112
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