B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation

Combined antiretroviral therapy (cART) for HIV-1 dramatically slows disease progression among HIV(+) individuals. Currently, lymphoma represents the main cause of death among HIV-1-infected patients. Detection of p17 variants (vp17s) endowed with B-cell clonogenic activity in HIV-1-seropositive pati...

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Vydáno v:Cancer Gene Ther
Hlavní autoři: Giagulli, Cinzia, Caccuri, Francesca, Zorzan, Simone, Bugatti, Antonella, Zani, Alberto, Filippini, Federica, Manocha, Ekta, D’Ursi, Pasqualina, Orro, Alessandro, Dolcetti, Riccardo, Caruso, Arnaldo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group US 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203498/
https://ncbi.nlm.nih.gov/pubmed/33093643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41417-020-00246-9
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