A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17

Recent data highlight the presence, in HIV-1-seropositive patients with lymphoma, of p17 variants (vp17s) endowed with B-cell clonogenicity, suggesting a role of vp17s in lymphomagenesis. We investigated the mechanisms responsible for the functional disparity on B cells between a wild-type p17 (refp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Giagulli, Cinzia, D’Ursi, Pasqualina, He, Wangxiao, Zorzan, Simone, Caccuri, Francesca, Varney, Kristen, Orro, Alessandro, Marsico, Stefania, Otjacques, Benoît, Laudanna, Carlo, Milanesi, Luciano, Dolcetti, Riccardo, Fiorentini, Simona, Lu, Wuyuan, Caruso, Arnaldo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529431/
https://ncbi.nlm.nih.gov/pubmed/28747658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06848-y
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