Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA

The sarco-plasmic reticulum calcium pump (SERCA) plays a critical role in the contraction-relaxation cycle of muscle. In cardiac muscle, SERCA is regulated by the inhibitor phospholamban. A new regulator, dwarf open reading frame (DWORF), has been reported to displace phospholamban from SERCA. Here,...

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Vydáno v:eLife
Hlavní autoři: Fisher, M'Lynn E, Bovo, Elisa, Aguayo-Ortiz, Rodrigo, Cho, Ellen E, Pribadi, Marsha P, Dalton, Michael P, Rathod, Nishadh, Lemieux, M Joanne, Espinoza-Fonseca, L Michel, Robia, Seth L, Zima, Aleksey V, Young, Howard S
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2021
Témata:
Biochemistry and Chemical Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203291/
https://ncbi.nlm.nih.gov/pubmed/34075877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65545
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