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Identification of ACE2 modifiers by CRISPR screening
SARS-CoV-2 infection is initiated by binding of the viral spike protein to its receptor, ACE2, on the surface of host cells. ACE2 expression is heterogeneous both in vivo and in immortalized cell lines, but the molecular pathways that govern ACE2 expression remain unclear. We now report high-through...
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| Publicado no: | bioRxiv |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8202422/ https://ncbi.nlm.nih.gov/pubmed/34127970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.06.10.447768 |
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