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ACE2 protein expression within isogenic cell lines is heterogeneous and associated with distinct transcriptomes

The membrane protein angiotensin-converting enzyme 2 (ACE2) is a physiologic regulator of the renin-angiotensin system and the cellular receptor for the SARS-CoV-2 virus. Prior studies of ACE2 expression have primarily focused on mRNA abundance, with investigation at the protein level limited by unc...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Sherman, Emily J., Emmer, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010730/
https://ncbi.nlm.nih.gov/pubmed/33791703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.26.437218
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