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GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells

In addition to driving specific gene expression profiles, transcriptional regulators are becoming increasingly recognized for their capacity to modulate chromatin structure. GATA6 is essential for the formation of definitive endoderm; however, the molecular basis defining the importance of GATA6 to...

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Publicat a:Cell Rep
Autors principals: Heslop, James A., Pournasr, Behshad, Liu, Jui-Tung, Duncan, Stephen A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202205/
https://ncbi.nlm.nih.gov/pubmed/34010638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109145
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