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Modeling inborn errors of hepatic metabolism using induced pluripotent stem cells

Inborn errors of hepatic metabolism are due to deficiencies commonly within a single enzyme as a consequence of heritable mutations in the genome. Individually such diseases are rare, but collectively they are common. Advances in genome wide association studies (GWAS) and DNA sequencing have helped...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Pournasr, Behshad, Duncan, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824724/
https://ncbi.nlm.nih.gov/pubmed/28818857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309199
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