Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy

Neuropathological observations in neurodegenerative synucleinopathies, including Parkinson disease, implicate a pathological role of α-synuclein accumulation in extranigral sites during the prodromal phase of the disease. In a transgenic mouse model of peripheral-to-central neuroinvasion and propaga...

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Udgivet i:Brain Commun
Main Authors: Ferreira, Nelson, Richner, Mette, van der Laan, Amelia, Bergholdt Jul Christiansen, Ida, Vægter, Christian B, Nyengaard, Jens R, Halliday, Glenda M, Weis, Joachim, Giasson, Benoit I, Mackenzie, Ian R, Jensen, Poul H, Jan, Asad
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202146/
https://ncbi.nlm.nih.gov/pubmed/34136810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcab104
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