Unrestrained Gα(i2) Signaling Disrupts Neutrophil Trafficking, Aging, and Clearance

Neutrophil trafficking, homeostatic and pathogen elicited, depends upon chemoattractant receptors triggering heterotrimeric G-protein Gα(i)βγ signaling, whose magnitude and kinetics are governed by RGS protein/Gα(i) interactions. RGS proteins typically limit Gα(i) signaling by reducing the duration...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yan, Serena Li-Sue, Hwang, Il-Young, Kamenyeva, Olena, Kabat, Juraj, Kim, Ji Sung, Park, Chung, Kehrl, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202015/
https://ncbi.nlm.nih.gov/pubmed/34135907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.679856
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