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AP-1 is a temporally regulated dual gatekeeper of reprogramming to pluripotency

Somatic cell transcription factors are critical to maintaining cellular identity and constitute a barrier to human somatic cell reprogramming; yet a comprehensive understanding of the mechanism of action is lacking. To gain insight, we examined epigenome remodeling at the onset of human nuclear repr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Markov, Glenn J., Mai, Thach, Nair, Surag, Shcherbina, Anna, Wang, Yu Xin, Burns, David M., Kundaje, Anshul, Blau, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201948/
https://ncbi.nlm.nih.gov/pubmed/34088849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2104841118
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