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Integrating regulatory DNA sequence and gene expression to predict genome-wide chromatin accessibility across cellular contexts

MOTIVATION: Genome-wide profiles of chromatin accessibility and gene expression in diverse cellular contexts are critical to decipher the dynamics of transcriptional regulation. Recently, convolutional neural networks have been used to learn predictive cis-regulatory DNA sequence models of context-s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioinformatics
Egile Nagusiak: Nair, Surag, Kim, Daniel S, Perricone, Jacob, Kundaje, Anshul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612838/
https://ncbi.nlm.nih.gov/pubmed/31510655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz352
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