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Coevolutionary phage training leads to greater bacterial suppression and delays the evolution of phage resistance

The evolution of antibiotic-resistant bacteria threatens to become the leading cause of worldwide mortality. This crisis has renewed interest in the practice of phage therapy. Yet, bacteria’s capacity to evolve resistance may debilitate this therapy as well. To combat the evolution of phage resistan...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Borin, Joshua M., Avrani, Sarit, Barrick, Jeffrey E., Petrie, Katherine L., Meyer, Justin R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201913/
https://ncbi.nlm.nih.gov/pubmed/34083444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2104592118
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