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Coevolutionary phage training leads to greater bacterial suppression and delays the evolution of phage resistance

The evolution of antibiotic-resistant bacteria threatens to become the leading cause of worldwide mortality. This crisis has renewed interest in the practice of phage therapy. Yet, bacteria’s capacity to evolve resistance may debilitate this therapy as well. To combat the evolution of phage resistan...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Borin, Joshua M., Avrani, Sarit, Barrick, Jeffrey E., Petrie, Katherine L., Meyer, Justin R.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201913/
https://ncbi.nlm.nih.gov/pubmed/34083444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2104592118
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