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The phosphate moiety of phosphoenolpyruvate does NOT contribute to allosteric regulation of liver pyruvate kinase by fructose-1,6-bisphosphate

A linked-function theory for allostery allows for a differentiation between those protein-ligand interactions that contribute the most to ligand binding and those protein-ligand interactions that contribute to the allosteric mechanism. This potential distinction is the basis for analogue studies use...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Arch Biochem Biophys
Main Authors: Chappell, Benjamin M., Fenton, Aron W.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201620/
https://ncbi.nlm.nih.gov/pubmed/33075302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108633
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