Загрузка...

Distinguishing the interactions in the fructose-1,6-bisphosphate binding site of human liver pyruvate kinase that contribute to allostery

In the study of allosteric proteins, understanding which effector/protein interactions contribute to allosteric activation is important both for designing allosteric drugs and for understanding allosteric mechanisms. The anti-hyperglycemic target, human liver pyruvate kinase (hL-PYK), binds its allo...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Biochemistry
Главные авторы: Ishwar, Arjun, Tang, Qingling, Fenton, Aron W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286843/
https://ncbi.nlm.nih.gov/pubmed/25629396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501426w
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!