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Evolutionary Comparative Analyses of DNA-Editing Enzymes of the Immune System: From 5-Dimensional Description of Protein Structures to Immunological Insights and Applications to Protein Engineering

The immune system is unique among all biological sub-systems in its usage of DNA-editing enzymes to introduce targeted gene mutations and double-strand DNA breaks to diversify antigen receptor genes and combat viral infections. These processes, initiated by specific DNA-editing enzymes, often result...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Ghorbani, Atefeh, Quinlan, Emma M., Larijani, Mani
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201067/
https://ncbi.nlm.nih.gov/pubmed/34135887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.642343
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