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APOBEC3G Regulation of the Evolutionary Race Between Adaptive Immunity and Viral Immune Escape Is Deeply Imprinted in the HIV Genome

APOBEC3G (A3G) is a host enzyme that mutates the genomes of retroviruses like HIV. Since A3G is expressed pre-infection, it has classically been considered an agent of innate immunity. We and others previously showed that the impact of A3G-induced mutations on the HIV genome extends to adaptive immu...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Borzooee, Faezeh, Joris, Krista D., Grant, Michael D., Larijani, Mani
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338068/
https://ncbi.nlm.nih.gov/pubmed/30687306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03032
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