The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity

In nonalcoholic steatohepatitis animal models, an increased lipid droplet size in hepatocytes is associated with fibrogenesis. Hepatocytes with large droplet (Ld-MaS) or small droplet (Sd-MaS) macrovesicular steatosis may coexist in the human liver, but the factors associated with the predominance o...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Ferri, Flaminia, Carotti, Simone, Carpino, Guido, Mischitelli, Monica, Cantafora, Alfredo, Molinaro, Antonio, Argenziano, Maria Eva, Parisse, Simona, Corsi, Alessandro, Riminucci, Mara, Lai, Quirino, Mennini, Gianluca, Spadetta, Gustavo, Pugliese, Francesco, Rossi, Massimo, Morini, Sergio, Gaudio, Eugenio, Ginanni Corradini, Stefano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200978/
https://ncbi.nlm.nih.gov/pubmed/34198853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116100
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