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Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events

BACKGROUND: Familial hypercholesterolemia (FH) may arise from deleterious monogenic variants in FH‐causing genes as well as from a polygenic cause. We evaluated the relationships between monogenic FH and polygenic hypercholesterolemia in influencing the long‐term response to therapy and the risk of...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: D’Erasmo, Laura, Minicocci, Ilenia, Di Costanzo, Alessia, Pigna, Giovanni, Commodari, Daniela, Ceci, Fabrizio, Montali, Anna, Brancato, Francesca, Stanca, Ilaria, Nicolucci, Antonio, Ascione, Andrea, Galea, Nicola, Carbone, Iacopo, Francone, Marco, Maranghi, Marianna, Arca, Marcello
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200757/
https://ncbi.nlm.nih.gov/pubmed/33890476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018932
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