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An Investigation into the Potential of Targeting Escherichia coli rne mRNA with Locked Nucleic Acid (LNA) Gapmers as an Antibacterial Strategy

The increase in antibacterial resistance is a serious challenge for both the health and defence sectors and there is a need for both novel antibacterial targets and antibacterial strategies. RNA degradation and ribonucleases, such as the essential endoribonuclease RNase E, encoded by the rne gene, a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Molecules
Κύριοι συγγραφείς: Goddard, Layla R., Mardle, Charlotte E., Gneid, Hassan, Ball, Ciara G., Gowers, Darren M., Atkins, Helen S., Butt, Louise E., Watts, Jonathan K., Vincent, Helen A., Callaghan, Anastasia J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2021
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200214/
https://ncbi.nlm.nih.gov/pubmed/34200016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26113414
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