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Identification and analysis of novel small molecule inhibitors of RNase E: Implications for antibacterial targeting and regulation of RNase E
Increasing resistance of bacteria to antibiotics is a serious global challenge and there is a need to unlock the potential of novel antibacterial targets. One such target is the essential prokaryotic endoribonuclease RNase E. Using a combination of in silico high-throughput screening and in vitro va...
Zapisane w:
Wydane w: | Biochem Biophys Rep |
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Główni autorzy: | , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Elsevier
2020
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7284133/ https://ncbi.nlm.nih.gov/pubmed/32548313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100773 |
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