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Towards Profiling of the G-Quadruplex Targeting Drugs in the Living Human Cells Using NMR Spectroscopy

Recently, the (1)H-detected in-cell NMR spectroscopy has emerged as a unique tool allowing the characterization of interactions between nucleic acid-based targets and drug-like molecules in living human cells. Here, we assess the application potential of (1)H and (19)F-detected in-cell NMR spectrosc...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Krafčík, Daniel, Ištvánková, Eva, Džatko, Šimon, Víšková, Pavlína, Foldynová-Trantírková, Silvie, Trantírek, Lukáš
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199861/
https://ncbi.nlm.nih.gov/pubmed/34205000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116042
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