The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions

G-quadruplex topologies of telomeric repeat sequences from vertebrates were investigated in the presence of molecular crowding (MC) mimetics, namely polyethylene glycol 200 (PEG), Ficoll 70 as well as Xenopus laevis egg extract by CD and NMR spectroscopy and native PAGE. Here, we show that the confo...

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Sonraí Bibleagrafaíochta
Main Authors: Hänsel, Robert, Löhr, Frank, Foldynová-Trantírková, Silvie, Bamberg, Ernst, Trantírek, Lukáš, Dötsch, Volker
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2011
Ábhair:
Structural Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141269/
https://ncbi.nlm.nih.gov/pubmed/21450807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr174
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