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Evaluation of the Stability of DNA i‐Motifs in the Nuclei of Living Mammalian Cells

C‐rich DNA has the capacity to form a tetra‐stranded structure known as an i‐motif. The i‐motifs within genomic DNA have been proposed to contribute to the regulation of DNA transcription. However, direct experimental evidence for the existence of these structures in vivo has been missing. Whether i...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Principais autores: Dzatko, Simon, Krafcikova, Michaela, Hänsel‐Hertsch, Robert, Fessl, Tomas, Fiala, Radovan, Loja, Tomas, Krafcik, Daniel, Mergny, Jean‐Louis, Foldynova‐Trantirkova, Silvie, Trantirek, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820743/
https://ncbi.nlm.nih.gov/pubmed/29266664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201712284
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