Synthesis and Antinociceptive Effect of Some Thiazole-Piperazine Derivatives: Involvement of Opioidergic System in the Activity

In this study, we aimed to design and synthesize novel molecules carrying both the thiazole and piperazine rings in their structures and to investigate their antinociceptive activity. Targeted compounds were obtained by reacting thiosemicarbazide derivative and appropriate 2-bromoacetophenone in eth...

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Vydáno v:Molecules
Hlavní autoři: Yücel, Nazlı Turan, Osmaniye, Derya, Kandemir, Ümmühan, Evren, Asaf Evrim, Can, Özgür Devrim, Demir Özkay, Ümide
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199615/
https://ncbi.nlm.nih.gov/pubmed/34199486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26113350
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