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Synthesis and Antinociceptive Effect of Some Thiazole-Piperazine Derivatives: Involvement of Opioidergic System in the Activity

In this study, we aimed to design and synthesize novel molecules carrying both the thiazole and piperazine rings in their structures and to investigate their antinociceptive activity. Targeted compounds were obtained by reacting thiosemicarbazide derivative and appropriate 2-bromoacetophenone in eth...

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Publicat a:Molecules
Autors principals: Yücel, Nazlı Turan, Osmaniye, Derya, Kandemir, Ümmühan, Evren, Asaf Evrim, Can, Özgür Devrim, Demir Özkay, Ümide
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199615/
https://ncbi.nlm.nih.gov/pubmed/34199486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26113350
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