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An Unbalanced Synaptic Transmission: Cause or Consequence of the Amyloid Oligomers Neurotoxicity?

Amyloid-β (Aβ) 1-40 and 1-42 peptides are key mediators of synaptic and cognitive dysfunction in Alzheimer’s disease (AD). Whereas in AD, Aβ is found to act as a pro-epileptogenic factor even before plaque formation, amyloid pathology has been detected among patients with epilepsy with increased ris...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Sciaccaluga, Miriam, Megaro, Alfredo, Bellomo, Giovanni, Ruffolo, Gabriele, Romoli, Michele, Palma, Eleonora, Costa, Cinzia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199544/
https://ncbi.nlm.nih.gov/pubmed/34206089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115991
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