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Fascin Inhibitors Decrease Cell Migration and Adhesion While Increase Overall Survival of Mice Bearing Bladder Cancers

SIMPLE SUMMARY: Fascin is an actin-bundling protein, and is highly expressed in metastatic tumor cells. Small molecule fascin inhibitors have been recently developed to block tumor cell migration, invasion, and metastasis. Here we have tested a new fascin inhibitor on bladder cancer cells, and showe...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Zhao, Zhankui, Wang, Yufeng, Zhang, J. Jillian, Huang, Xin-Yun
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199464/
https://ncbi.nlm.nih.gov/pubmed/34070777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112698
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