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Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity

Fascin protein is the main actin-bundling protein in filopodia and invadopodia, which are critical for tumor cell migration, invasion, and metastasis. Small-molecule fascin inhibitors block tumor invasion and metastasis and increase the overall survival of tumor-bearing mice. Here, we report a findi...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Wang, Yufeng, Song, Mei, Liu, Ming, Zhang, Guoan, Zhang, Xian, Li, Ming O., Ma, Xiaojing, Zhang, J. Jillian, Huang, Xin-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050791/
https://ncbi.nlm.nih.gov/pubmed/33826900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108948
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