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Differential Effects of Fkbp4 and Fkbp5 on Regulation of the Proopiomelanocortin Gene in Murine AtT-20 Corticotroph Cells

The hypothalamic-pituitary-adrenal axis is stimulated in response to stress. When activated, it is suppressed by the negative feedback effect of glucocorticoids. Glucocorticoids directly inhibit proopiomelanocortin (Pomc) gene expression in the pituitary. Glucocorticoid signaling is mediated via glu...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kageyama, Kazunori, Iwasaki, Yasumasa, Watanuki, Yutaka, Niioka, Kanako, Daimon, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199270/
https://ncbi.nlm.nih.gov/pubmed/34072036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115724
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