Therapeutic Targeting of Protein Disulfide Isomerase PDIA1 in Multiple Myeloma

SIMPLE SUMMARY: Multiple myeloma (MM) is a cancer of antibody-producing plasma cells that remains incurable. These cells heavily depend on protein disulfide isomerase, PDIA1, for folding and structural integrity of antibodies and other secretory proteins to avoid unresolvable stress caused if they r...

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Publicat a:Cancers (Basel)
Autors principals: Hasipek, Metis, Grabowski, Dale, Guan, Yihong, Alugubelli, Raghunandan Reddy, Tiwari, Anand D., Gu, Xiaorong, DeAvila, Gabriel A., Silva, Ariosto S., Meads, Mark B., Parker, Yvonne, Lindner, Daniel J., Saunthararajah, Yogen, Shain, Kenneth H., Maciejewski, Jaroslaw P., Reu, Frederic J., Phillips, James G., Jha, Babal K.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198550/
https://ncbi.nlm.nih.gov/pubmed/34071205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112649
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