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Treg-Resistant Cytotoxic CD4(+) T Cells Dictate T Helper Cells in Their Vicinity: TH17 Skewing and Modulation of Proliferation
Cytotoxic CD4(+) T cells (CD4 CTL) are terminally differentiated T helper cells that contribute to autoimmune diseases, such as multiple sclerosis. We developed a novel triple co-culture transwell assay to study mutual interactions between CD4 CTL, conventional TH cells, and regulatory T cells (Treg...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8198086/ https://ncbi.nlm.nih.gov/pubmed/34073458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115660 |
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