Cytomegalovirus infection exacerbates autoimmune mediated neuroinflammation

Cytomegalovirus (CMV) is a latent virus which causes chronic activation of the immune system. Here, we demonstrate that cytotoxic and pro-inflammatory CD4(+)CD28(null) T cells are only present in CMV seropositive donors and that CMV-specific Immunoglobulin (Ig) G titers correlate with the percentage...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Vanheusden, Marjan, Broux, Bieke, Welten, Suzanne P. M., Peeters, Liesbet M., Panagioti, Eleni, Van Wijmeersch, Bart, Somers, Veerle, Stinissen, Piet, Arens, Ramon, Hellings, Niels
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428769/
https://ncbi.nlm.nih.gov/pubmed/28386103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00645-3
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