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EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance

SIMPLE SUMMARY: Growth factors are hormone-like molecules able to promote division and migration of normal cells, but cancer captured the underlying mechanisms to unleash tumor growth and metastasis. Here we review the epidermal growth factor (EGF), which controls epithelial cells, the precursors of...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Uribe, Mary Luz, Marrocco, Ilaria, Yarden, Yosef
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197917/
https://ncbi.nlm.nih.gov/pubmed/34206026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112748
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