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Relationship of DUX4 and target gene expression in FSHD myocytes

Facioscapulohumeral dystrophy (FSHD) is associated with upregulation of the DUX4 transcription factor and its target genes. However, low frequency DUX4 upregulation in patient myocytes is difficult to detect and examining the relationship and dynamics of DUX4 and target gene expression has been chal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Mutat
Hauptverfasser: Chau, Jonathan, Kong, Xiangduo, Nguyen, Nam, Williams, Katherine, Tawil, Rabi, Kiyono, Tohru, Mortazavi, Ali, Yokomori, Kyoko
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197291/
https://ncbi.nlm.nih.gov/pubmed/33502067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.24171
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