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Relationship of DUX4 and target gene expression in FSHD myocytes

Facioscapulohumeral dystrophy (FSHD) is associated with upregulation of the DUX4 transcription factor and its target genes. However, low frequency DUX4 upregulation in patient myocytes is difficult to detect and examining the relationship and dynamics of DUX4 and target gene expression has been chal...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Chau, Jonathan, Kong, Xiangduo, Nguyen, Nam, Williams, Katherine, Tawil, Rabi, Kiyono, Tohru, Mortazavi, Ali, Yokomori, Kyoko
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197291/
https://ncbi.nlm.nih.gov/pubmed/33502067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.24171
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