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Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nuclei
FSHD is characterized by the misexpression of DUX4 in skeletal muscle. Although DUX4 upregulation is thought to be the pathogenic cause of FSHD, DUX4 is lowly expressed in patient samples, and analysis of the consequences of DUX4 expression has largely relied on artificial overexpression. To better...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7224571/ https://ncbi.nlm.nih.gov/pubmed/32365093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008754 |
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