Single-nucleus RNA-seq of differentiating human myoblasts reveals the extent of fate heterogeneity

Myoblasts are precursor skeletal muscle cells that differentiate into fused, multinucleated myotubes. Current single-cell microfluidic methods are not optimized for capturing very large, multinucleated cells such as myotubes. To circumvent the problem, we performed single-nucleus transcriptome analy...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Zeng, Weihua, Jiang, Shan, Kong, Xiangduo, El-Ali, Nicole, Ball, Alexander R., Ma, Christopher I-Hsing, Hashimoto, Naohiro, Yokomori, Kyoko, Mortazavi, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137429/
https://ncbi.nlm.nih.gov/pubmed/27566152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw739
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