Photoactivation of TGFβ/SMAD signaling pathway ameliorates adult hippocampal neurogenesis in Alzheimer’s disease model

BACKGROUND: Adult hippocampal neurogenesis (AHN) is restricted under the pathological conditions of neurodegenerative diseases, especially in Alzheimer’s disease (AD). The drop of AHN reduces neural circuit plasticity, resulting in the decrease of the generation of newborn neurons in dentate gyrus (...

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Publicado en:Stem Cell Res Ther
Autores principales: Wu, Xiaolei, Shen, Qi, Zhang, Zhan, Zhang, Di, Gu, Ying, Xing, Da
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196501/
https://ncbi.nlm.nih.gov/pubmed/34116709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02399-2
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