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Photoactivation of TGFβ/SMAD signaling pathway ameliorates adult hippocampal neurogenesis in Alzheimer’s disease model

BACKGROUND: Adult hippocampal neurogenesis (AHN) is restricted under the pathological conditions of neurodegenerative diseases, especially in Alzheimer’s disease (AD). The drop of AHN reduces neural circuit plasticity, resulting in the decrease of the generation of newborn neurons in dentate gyrus (...

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Bibliografische gegevens
Gepubliceerd in:Stem Cell Res Ther
Hoofdauteurs: Wu, Xiaolei, Shen, Qi, Zhang, Zhan, Zhang, Di, Gu, Ying, Xing, Da
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196501/
https://ncbi.nlm.nih.gov/pubmed/34116709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02399-2
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