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Photoactivation of TGFβ/SMAD signaling pathway ameliorates adult hippocampal neurogenesis in Alzheimer’s disease model

BACKGROUND: Adult hippocampal neurogenesis (AHN) is restricted under the pathological conditions of neurodegenerative diseases, especially in Alzheimer’s disease (AD). The drop of AHN reduces neural circuit plasticity, resulting in the decrease of the generation of newborn neurons in dentate gyrus (...

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Podrobná bibliografie
Vydáno v:Stem Cell Res Ther
Hlavní autoři: Wu, Xiaolei, Shen, Qi, Zhang, Zhan, Zhang, Di, Gu, Ying, Xing, Da
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196501/
https://ncbi.nlm.nih.gov/pubmed/34116709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02399-2
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