Amnion epithelial cells are an effective source of factor H and prevent kidney complement deposition in factor H-deficient mice

Complement factor H (FH) is the main plasma regulator of the alternative pathway of complement. Genetic and acquired abnormalities in FH cause uncontrolled complement activation amplifying, with the consequent accumulation of complement components on the renal glomeruli. This leads to conditions suc...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Stem Cell Res Ther
Main Authors: Casiraghi, Federica, Ordonez, Pamela Yossenaidy Rodriguez, Azzollini, Nadia, Todeschini, Marta, Rottoli, Daniela, Donadelli, Roberta, Gramignoli, Roberto, Benigni, Ariela, Noris, Marina, Remuzzi, Giuseppe
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Short Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8194190/
https://ncbi.nlm.nih.gov/pubmed/34112227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02386-7
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki