Insights into the Effects of Complement Factor H on the Assembly and Decay of the Alternative Pathway C3 Proconvertase and C3 Convertase

The activated fragment of C3 (C3b) and factor B form the C3 proconvertase (C3bB), which is cleaved by factor D to C3 convertase (C3bBb). Older studies (Conrad, D. H., Carlo, J. R., and Ruddy, S. (1978) J. Exp. Med. 147, 1792–1805; Pangburn, M. K., and Müller-Eberhard, H. J. (1978) Proc. Natl. Acad....

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Bettoni, Serena, Bresin, Elena, Remuzzi, Giuseppe, Noris, Marina, Donadelli, Roberta
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825022/
https://ncbi.nlm.nih.gov/pubmed/26903516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693119
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